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Permanent members

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Christelle Hureau

Team leader

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Charlène ESMIEU

Associate researcher

​ (+33) 5 61 33 31 20

charlene.esmieu@lcc-toulouse.fr

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Emilie MATHIEU

Associate researcher

 (+33) 5 61 33 31 21

emilie.mathieu@lcc-toulouse.fr

Technical staff 
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Maritie GARNIER

Non-permanent members

Post-Doc

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Enrico FALCONE

Interaction of lanthanide(III) ions and complexes with amyloid-β peptides

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Antoine BAUDIN

Study of the modulation of the fibrillar assembly of amyloid-β peptides by polyanionic molecules

Mélanie ROSSOTTI

Mesure d'affinité du cuivre pour différents sites protéiques par compétition

PhD Students

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Barbara MARINHO-BARBOSA

Evaluation and mechanistic studies of new N-acylhydrazones metallophores in the context of Alzheimer's Diseas

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David SCHMITT

Study of the auto-assembly of amylin and amyloid-beta peptides

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Adèle BRISON

Study of the auto-assembly of amylin and amyloid-beta peptides in the presence of porphyrins

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Romain CARRASCO

Synthesis and evaluation of fluorescent copper's ligands for the therapy by chelation in the context of Alzheimer's disease

Technical staff

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Alexandre FONDER

Structural and functional modelling of LPMO using peptide-copper complexes

Undergraduates

Morgane NEVEU
Master 2

Honorine NGOBO
Master 2

Marie BAGREL
Master 2

Former team members

1988-2023 - Research Director

Former post-doctoral researchers

Since 2016

Laurent SABATER

Patrick MALIKIDOGO

Inga RELICH

Nina WEZYNFELD

Clémence CHEIGNON

Simon COMPANYS

Djamilla GUETTAS

2020-2021 - Zinc and Alzheimer's disease: impact on aggregation and in the development of therapeutic strategies

2020-2021 - Synthesis and characterization of new ligands for copper ions in the context of AD chelation therapy

2020-2021 - Study of MRI markers for the detection of amylin aggregates involved in Type II diabetes

2019  -   Copper coordination to model peptides of Ctr1 and Ctr2 transporters: electrochemical and NMR studies

2017 - Study of the impact of peptide oxidation of amyloid-β on its aggregation capabilities

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2017-2018  -  2-aryl-Benzothiazole probes for the detection of amyloid aggregates

Elena ATRIAN-BLASCO

Carine MAALIKI

Mireia TOMAS I GINER

Melissa DEL BARRIO REDONDO

2016-2019   -   Study of selective chelators in Alzheimer's disease

2016  -  New recognition platforms for amyloid peptide oligomers

2015   -   Study of reactive oxygen species production by amyloid-β peptides truncated at positions 4 and 11

2015-2016  -  Study of reactive oxygen species production by Cu-amyloid-β systems as a function of amyloid-β peptide aggregation

Former PhD Students

Since 2016

Margot LEFEVRE

Antoine TRONNET

Tiffany RUNDSTADLER

Xudong LIN

Raul BALDERRAMA

Ewelina STEFANIAK

Amandine VINCENT

Sara AYALA

Alexandre POCINHO

Valentina BORGHESANI

Amandine CONTE-DABAN

2022-2025   -    Study of peptides assembly with or without the addition of polyoxometalates or polyphosphates

2021-2024   -    Synthesis and studies of new inorganic pro-drugs based on hybrid organic/peptidic scaffold in the context of Alzheimer Disease

2021-2024   -    Design, synthesis and study of artificial metallopeptidases in the context of Alzheimer's disease

2020-2023   -    Synthesis of traceable copper I chelating ligand for chelation therapy in Alzheimer's disease 

2018-2022   -    â€‹Elucidation of mechanisms at the origin of Alzheimer's disease 

2018-2022   -    Polymeric analog of antimicrobial peptides with anti-Clostridium difficile therapeutic potential

2018-2022   -   G-quadruplex ligands of nucleic acids: modeling, synthesis and antiviral activity

2018-2021   -   Synthesis and studies of compounds targeting the aggregation of amyloid-beta peptide

2019   -   Peptidomimetic ligands for the chelation of Cu(II)

2016-2017  -   Coordination of Cu(II) ions to peptides for SOD activity

2018-2019   -   Co-aggregation of amyloid peptides

2014-2018   -   Role of Zn ions and chaperone proteins in the aggregation of different forms of amyloid-β peptide

2014-2018   -   Optimization of molecules for recognition of oligomeric forms of amyloid-β peptides

2015-2018   -   Impact of Zn ions in the aggregation of different forms of amyloid-β peptide

2014-2017  -  Role of Cu and Zn ions in the aggregation and toxicity of metal complexes of amyloid-β peptide: mechanistic and therapeutic aspects

Former technical staff 

Michele CODEVILLE

Thomas RIVIERE

Former undergraduate trainees

Since 2016

Noémie CLAVEL
Master 1

Armand SABATER
Bellevue Student

Alexandre FONDER
Master 2

Cisley ALLUE
INP Student

Zoé BUHAGIAR
INP Student

Louane BANCHERI
Master 1

Célia LORENZATO
BTS Student

Emma VIERA
Licence 2

Diane LE PICHON
Licence 2

Camille BLANC
Bachelor 3

Antoine CAILLAT
Master 2

Lielou LANTIGNER
Master 2

Charlotte APARICI
Master 2

Mélanie MASSOT
Master 2

Clara LAHON
BTS Student

Lucas GANIMEDE
Engineer student

Max PERLOT
Master 1

Adèle BRISON
Master 1

Lauriane ORIOL
Licence 3

Anastasia GOLOVETSKI
Master

Stephanie LEON QUINOMEZ
Bachelor

Camille MONTAGNAC
ENS Student

Rufus MITCHELL
Erasmus

Jose ROSALES
Licence 3

Liz LAGARDE
Master 2

Nicolas GOUZENES
BTS Student

Laura ANDOLFO
Master 2

Thomas PICHON
Master 2

Ingrid VALLARD
Master 2

Arnaud GILLIS
Master 2

Guillaume FERRAND
Medical Student

François GU
ENS Student

Tiriana TCHONG
Master 2

Jennifer BONNAL
Licence 3

Nicolas JEAN-BART
ENS student

Lucie CHANU
Engineer student

Gwenola MAILLARD
Master 2

Quentin GROS
Master 1

Agnès SIPOS
ENS student

Alzheimer, Amyloids and BioInorganic Chemistry

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Laboratoire de Chimie de Coordination, CNRS,

Université Paul Sabatier

205 Route de Narbonne, Toulouse, France

lcc.teamf@gmail.com

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©2021 par LCC - Toulouse - Équipe F

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