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Emilie MATHIEU

Associate researcher

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Research

My principal project focuses on developing artificial lanthanide enzymes as models of lanthanide methanol dehydrogenases. We aim to deepen our understanding of the interactions between lanthanide ions and peptides, as well as the role played by the metal ion in the catalytic activity of the enzyme.

I am also involved in two side projects: (i) the investigation of the ability of Ln-complexes to modulate the amyloid-β assembly process, and the characterization of the interactions responsible for it; (ii) the development of copper catalysts based on amyloid peptides for Michael addition reaction

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CV

EXPERIENCES

Since October 2021 - Associate researcher

LCC, Toulouse, France - Team ALAMBIC

Keywords: enzyme mimics, Ln(III), luminescence

September 2020 - July 2021 - Post-doctoral fellow
LCC, Toulouse, France - Group of Prof. Christelle Hureau
Keywords: catalysis, Cu(II), amyloids, Michael addition, C-C bond formation


May 2018 - May 2020 - Post-doctoral fellow
Uppsala University, Uppsala, Sweden - Group of Prof. Eszter Borbas
Keywords: photo-induced electron transfer, Ln(III) complexes, spectroscopy, electrochemistry


September 2017 - March 2018 - Post-doctoral fellow
Ecole Normale Supérieure, Paris, France - Group of Prof. Clotilde Policar
Keywords: X-ray fluorescence imaging, subcellular distribution, Mn(II) complex

September 2014 - September 2017 - PhD
Sorbonne University, Paris, France - Supervisor: Prof. Clotilde Policar and Dr. Nicolas Delsuc

Keywords: superoxide dismutase mimics, Mn(II), oxidative stress, chronic inflammation, bioavailability


October 2016 - December 2016:

Michigan University, Ann Arbor, USA - Group of Prof. Vincent Pecoraro
Keywords: superoxide dismutase mimes, rational enzyme design, Cu(II)


November 2013 - July 2014 - Pre-doctoral internship
Simon Fraser University, Vancouver, Canada - Group of Prof. Tim Storr
Keywords: organic synthesis, Cu(II) complexes, oxidative stress, amyloid, Alzheimer's disease

DIFFUSION ACTIONS

 

● Speaker for Declics (November 2020) - Virtual meeting with high school students.
● National and International Chemistry Olympiads (ICO / CNO) (2014 - 2016)
- organic chemistry courses
- supervision of practical work
- writing of the organic chemistry topic for the national selection of the IOC (2016)
● Candidate for Ma thèse en 180 secondes Thesis (2016) - Regional selection of Sorbonne University
● Conducting workshops for the general public at the Nuit des Sciences et des Lettres (ENS, 2016), Fêtes de la Science (SU, 2015), and Science RendezVous (SFU, 2014)

Publications

You will find all my publications with the following link: https://orcid.org/0000-0002-9313-8679

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