2024
A widespread family of ribosomal peptide metallophores involved in bacterial adaptation to metal stress
L. Leprevost, S. Jünger, G. Lippens, C. Guillaume, G. Sicoli, L. Oliveira, E. Falcone, E. de Santis, A. Rivera-Millot, G. Billon, F. Stellato, C. Henry, R. Antoine, S. Zirah, S. Dubiley, Y. Li, F. Jacob-Dubuisson, Proceeding of National Academy of Sciences 2024
When Metal Complexes Evolve, and a Minor Species is the Most Active: the Case of Bis(Phenanthroline)Copper in the Catalysis of Glutathione Oxidation and Hydroxyl Radical Generation
E. Falcone+, V. Vigna+, H. Schueffl, F. Stellato, B. Vileno,
M. Bouraguba, G. Mazzone, O. Proux, S. Morante, P. Heffeter,
E. Sicilia+,* and P. Faller*, Angew. Chem.int., 2024
Next-generation Cu(II) selective peptide shuttles prevent Cu(Aβ)-induced toxicity and microglial activation in organotypic hippocampal slices
Bioinorganic Chemistry of Copper: From Biochemistry to Pharmacology
A.M. Da Costa Ferreira, C. Hureau, G. Facchin, Inorganics 2024
Restoring cellular copper homeostasis in Alzheimer disease: a novel peptide shuttle is internalized by an ATP-dependent endocytosis pathway involving Rab5- and Rab14-endosomes
M. Okafor, O. Champomier, L. Raibaut, S. Ozkan, N. El Kholti, S. Ory, S. Chasserot-Golaz, S. Gasman, C. Hureau, P. Faller* N. Vitale*, Front. Mol. Biosci., 2024
Rationally designed Cu(I) ligand to prevent CuAb-generated ROS production in the Alzheimer's Disease context
C. Rulmont, J.-L. Stigliani, C. Hureau, C. Esmieu*, Inorg. Chem. 2024
Next-generation Cu(II) selective peptide shuttles prevent Cu(Aβ)-induced toxicity and microglial activation in organotypic hippocampal slices
Bioinorganic Chemistry of Copper: From Biochemistry to Pharmacology
A.M. Da Costa Ferreira, C. Hureau, G. Facchin, Inorganics 2024
Restoring cellular copper homeostasis in Alzheimer disease: a novel peptide shuttle is internalized by an ATP-dependent endocytosis pathway involving Rab5- and Rab14-endosomes
M. Okafor, O. Champomier, L. Raibaut, S. Ozkan, N. El Kholti, S. Ory, S. Chasserot-Golaz, S. Gasman, C. Hureau, P. Faller* N. Vitale*, Front. Mol. Biosci., 2024
Rationally designed Cu(I) ligand to prevent CuAb-generated ROS production in the Alzheimer's Disease context
C. Rulmont, J.-L. Stigliani, C. Hureau, C. Esmieu*, Inorg. Chem. 2024
2023
Redox processes in Cu-binding proteins: the “in-between” states in intrinsically disordered peptides
E. Falcone, C. Hureau, Chem. Soc. Rev. 2023
Reduced Schiff-base derivatives to stop reactive oxygen species production by the Cu(Ab) species: a structure-activity relationship
Synthesis, Characterization, and Biological Properties of the Copper(II) Complexes with Novel Ligand: N-[4-({2-[1-(pyridin-2-yl)ethylidene]hydrazinecarbothioyl}amino)phenyl]acetamide
R. Rusnac, O. Garbuz, Y. Chumakov, V. Tsapkov, C. Hureau, D. Istrati, A. Gulea, Inorganics 2023
Effect of Metal Environment and Immobilization on the catalytic activity of a Cu Superoxide Dismutase Mimic
The Critical Role of Ligand Flexibility on the Activity of Free and Immobilized Mn Superoxide Dismutase Mimics
LPMO-like activity of bioinspired copper complexes: from model substrate to extended polysaccharides
Biomimetic catalysis of nitrite reductase enzyme using copper complexes in chemical and electrochemical reduction of nitrite
Oxidative Damages on the Alzheimer's related-Ab peptide alters its ability to assemble
C. Cheignon, F. Collin, L. Sabater, C. Hureau, Antioxidants 2023
Interfacial behaviour of oligodeoxynucleotides prone to G-quadruplex formation on negatively charged electrode surface monitored by electrochemical probes
Ability of Azathiacyclen Ligands to Stop Cu(Aβ)-Induced Production of Reactive Oxygen Species: [3N1S] is the Right Donor Set
K. P. Malikidogo, M. Drommi, E. Atrián-Blasco, J. Hormann, N. Kulak, C. Esmieu, C. Hureau, Chem. Eur. J. 2023
2022
Deciphering RNA G-quadruplex function during the early steps of HIV-1 infection
Synthesis, characterization and superoxide dismutase activity of a biomimetic Mn(III) complex covalently anchored to mesoporous silica
M. Richezzi, C. Palopoli, C. Hureau, S. R. Signorella, J. Inorg. Biochem. 2022
Development of Cu(ii)-specific peptide shuttles capable of preventing Cu–amyloid beta toxicity and importing bioavailable Cu into cells
M. Okafor, P. Gonzalez, P. Ronot, I. E. Masoudi, A. Boos, S. Ory, S. Chasserot-Golaz, S. Gasman, L. Raibaut, C. Hureau, N. Vitale, P. Faller, Chem.Sci. 2022
Sequence–Activity Relationship of ATCUN Peptides in the Context of Alzheimer’s Disease
M. Lefèvre, K. P. Malikidogo, C. Esmieu, C. Hureau, Molecules 2022
Why the Ala-His-His Peptide Is an Appropriate Scaffold to Remove and Redox Silence Copper Ions from the Alzheimer’s-Related Aβ Peptide
Versatile Activity of a Copper(II) Complex Bearing a N4-Tetradentate Schiff Base Ligand with Reduced Oxygen Species
Keggin-type polyoxometalates as Cu(II) chelators in the context of Alzheimer's disease
Role of Metal Ions in Alzheimer's Disease:
Mechanistic Aspects Contributing to Neurotoxicity
C. Hureau, in Alzheimer’s Disease: Recent Findings in Pathophysiology, Diagnostic and Therapeutic Modalities; Govindaraju, T., Ed.; The Royal Society of Chemistry, 2022
2021
Hybrid Bis-Histidine Phenanthroline-Based Ligands to Lessen Aβ-Bound Cu ROS Production: An Illustration of Cu(I) Significance
M. Drommi, C. Rulmont, C. Esmieu, C. Hureau, Molecules, 2021, 26, 7630
A Water-Soluble Peptoid Chelator that Can Remove Cu2+ from Amyloid-β Peptides and Stop the Formation of Reactive Oxygen Species Associated with Alzheimer's Disease
A. E. Behar, L. Sabater, M. Baskin, C. Hureau, G. Maayan Angew. Chem. Int. Ed., 2021, early view
Copper Imbalance in Alzheimer’s Disease and Its Link with the Amyloid Hypothesis: Towards a Combined Clinical, Chemical, and Genetic Etiology
R. Squitti,P. Faller, C. Hureau, A. Granzotto, A. R. White, K. P. Kepp, J. Alzheimer's Dis., 2021, 83 (1), 23-41
Measurement of Interpeptidic CuII Exchange Rate Constants of CuII-Amyloid-β Complexes to Small Peptide Motifs by Tryptophan Fluorescence Quenching
Cheryle N. Beuning, Luca J. Zocchi, Kyangwi P. Malikidogo, Charlène Esmieu, Pierre Dorlet, Debbie C. Crans, and Christelle Hureau, Inorg. Chem. 2021, 60, 11, 7650–7659
SARS-CoV-2 Nsp3 unique domain SUD interacts with
guanine quadruplexes and G4-ligands inhibit this
interaction
M. Lavigne, O. Helynck, P. Rigolet, R. Boudria-Souilah, M. Nowakowski, B. Baron, S. Brülé, S. Hoos, B. Raynal,
L. Guittat, C. Beauvineau, S. Petres, A. Granzhan, J. Guillon, G. Pratviel, M.-P. Teulade-Fichou, P. England, J.-L. Mergny, H. Munier-Lehmann, Nucleic Acids Res., 2021, 49, 13, 7695–7712.
Publications 2015-2020
You will find below the bibliography of our articles published before 2021.