Lucie DE CREMOUX
PhD student
CV
EDUCATION
2017-2018 : Master 2 of Organic Chemistry and Life Sciences, University of Bordeaux, Talence
Organic chemistry, chemical biology, medicinal chemistry, pharmacology.
2016-2017 : Master 1 of Organic Chemistry and Life Sciences,University of Bordeaux, Talence
Organic chemistry, Chemical biology, Medicinal chemistry, Pharmacology, Medical imaging techniques.
2015-2016 : Licence 3 of Chemistry, University of Bordeaux, Talence
Organic, inorganic and analytical chemistry
2014-2015 : DUT in synthetic and analytical chemistry, University of Paris-Sud, Orsay
General, analytical, organic and inorganic chemistry, chemical engineering
INTERNSHIPS
PROFESSIONAL EXPERIENCE
February 2018-June 2018 - Measuring the one carbon metabolism: validation of a method to simultaneously measure multiple molecules related to one carbon metabolism, Chalmers Mass Spectrometry Infrastructure, Göteborg, Sweden, Sample preparation from plasma or blood, characterization and method validation by mass spectrometry (LC-MS, LC-MSMS, GC-MS)
January 2017-February 2017
Alzheimer's disease: synthesis of a model peptide of the Tau protein, Institute of Molecular Sciences, Bordeaux
Organic and peptide synthesis, Purification by HPLC, Characterization by Mass Spectrometry
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April 2016-July 2016
Development of novel fluorogenic chemical reporter for the imaging of biomolecules, Aquitaine Institute of Cognitive and Integrative Neurosciences, Bordeaux - Organic synthesis, characterization of molecules by proton, carbon, silicon and fluorine NMR, and mass
May 2015-July 2015
Development of new chemical probes for glycome imaging, Aquitaine Institute of Cognitive and Integrative Neuroscience, Bordeaux - Organic synthesis, NMR, IR and mass characterization of molecules, fluorescence measurements
June 2019-Present
Study engineer in physicochemical and biochemical analyses at the LCC (CNRS), Toulouse.
Study of β-amyloid peptide aggregation kinetics by fluorescence in the context of Alzheimer's disease research.
Aggregation: preparation of plaques, purification of Aβ peptides by FPLC, kinetics by fluorescence, titration by UV-Visible, visualization of fibers by TEM, data processing
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January 2019-May 2019
Laboratory technician at Agrobio, Rennes. - Sample preparation, Analyses by UV-Visible spectroscopy, Analyses by liquid chromatography (HPLC)
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Publication
C. Favre, L. de Cremoux, J. Badaut, F. Friscourt, Sydnone Reporters for Highly Flurorogenic Copper-Free Click Ligations, J. Org. Chem, 83: 2058−2066, 2018
Project
Participation to the ERC (European Council Research) project: “AlzINK, Alzheimer’s disease & Zinc : The missing link ?” leaded by Christelle Hureau.